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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC1A6
All Species:
10
Human Site:
S545
Identified Species:
27.5
UniProt:
P48664
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48664
NP_005062.1
564
61565
S545
S
L
G
K
P
Y
K
S
L
M
A
Q
E
K
G
Chimpanzee
Pan troglodytes
XP_001146398
542
59526
K520
V
I
E
E
N
E
M
K
K
P
Y
Q
L
I
A
Rhesus Macaque
Macaca mulatta
XP_001094417
542
59560
K520
V
I
E
E
N
E
M
K
K
P
Y
Q
L
I
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O35544
561
60766
S542
S
L
G
K
P
Y
K
S
L
M
A
Q
E
K
G
Rat
Rattus norvegicus
O35921
561
60697
S542
S
L
G
K
P
Y
K
S
L
M
A
Q
A
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418178
546
59898
S525
A
G
I
V
E
H
L
S
R
Q
E
L
D
A
Q
Frog
Xenopus laevis
NP_001083306
542
59629
K520
V
I
E
E
N
E
M
K
K
P
Y
Q
L
I
S
Zebra Danio
Brachydanio rerio
NP_001103173
560
60844
P540
V
I
E
E
N
E
K
P
Y
Q
L
I
C
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10901
503
54657
K485
S
I
A
M
N
D
E
K
R
Q
L
A
V
Y
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.9
66.1
N.A.
N.A.
95.2
94.6
N.A.
N.A.
72.8
65
65.2
N.A.
N.A.
N.A.
44.3
N.A.
Protein Similarity:
100
81.3
81.5
N.A.
N.A.
96.9
96.6
N.A.
N.A.
84.4
80.8
80.1
N.A.
N.A.
N.A.
63.1
N.A.
P-Site Identity:
100
6.6
6.6
N.A.
N.A.
100
93.3
N.A.
N.A.
6.6
6.6
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
20
20
N.A.
N.A.
100
93.3
N.A.
N.A.
26.6
20
26.6
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
0
0
0
0
0
0
0
34
12
12
12
23
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% C
% Asp:
0
0
0
0
0
12
0
0
0
0
0
0
12
0
0
% D
% Glu:
0
0
45
45
12
45
12
0
0
0
12
0
23
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
34
0
0
0
0
0
0
0
0
0
0
0
34
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
56
12
0
0
0
0
0
0
0
0
12
0
34
0
% I
% Lys:
0
0
0
34
0
0
45
45
34
0
0
0
0
34
0
% K
% Leu:
0
34
0
0
0
0
12
0
34
0
23
12
34
0
0
% L
% Met:
0
0
0
12
0
0
34
0
0
34
0
0
0
0
0
% M
% Asn:
0
0
0
0
56
0
0
0
0
0
0
0
0
0
12
% N
% Pro:
0
0
0
0
34
0
0
12
0
34
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
34
0
67
0
12
12
% Q
% Arg:
0
0
0
0
0
0
0
0
23
0
0
0
0
0
0
% R
% Ser:
45
0
0
0
0
0
0
45
0
0
0
0
0
0
12
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
45
0
0
12
0
0
0
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
34
0
0
12
0
34
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _